ملخص: In this paper, the authors review the mechanisms of acute deterioration and sudden death caused by colloid cysts (CCs). These dreaded events are widely recognized complications of CC, however the mechanism(s) in cause has been subject to controversy.Increased intracranial pressure (ICP) is a common event associated with many cerebral disorders, including colloid cysts, though compensatory mechanisms may allow ICP to remain at normal levels. However, a compensated system might decompensate for many factors such as intracranial haemorrhage, acute hydrocephalus, brain oedema, or an increase in sagittal sinus pressure (SSP). The sagittal sinus in adults with brain tumours appears to respond unpredictably when ICP increases and in some patients, when ICP increased the SSP increased too due to the fact that their sinuses collapse.We therefore speculate that the mechanism of acute deterioration and sudden death is a multifactorial and dynamic process, in which the increase in sagittal sinus pressure would appear to be an important element. It seems possible that acute deterioration is initiated by an increase in sagittal sinus pressure, which provokes acute brain swelling, with a series of often-irreversible events, leading to sudden death.Since the majority of cases of acute deterioration and death are due to CCs of the third ventricle, the authors suggest that surgical resection should be carried out on diagnosed CCs measuring over 1 cm, because sudden death has not been reported as having been caused by colloid cysts measuring less than this dimension.

لغة: إنجليزية